Scientific Program

Wed

Thu

Fri

Sat

Wednesday, May 7, 2025

Breast Cancer

08:00 am

Welcome Adress of the Hosts and Greeting Words
J.-U. Blohmer and J. Sehouli

Greeting Words
Prof. Dr. Martin E. Kreis
Medical Director of the Charité

Presidential Lecture

08:05 am
New Strategies for the Treatment of ER+/HER2-Endocrine-resistant Breast Cancer
M. Goetz
08:30 am

Live Surgery from 2 operating rooms

Moderation: M. Karsten, S. Paepke

  • Total Breast Reconstruction with AFT
  • Conversion from Implant to AFT
  • Various Techniques of BCS and SNB
  • Gender-affirming Breast Surgery
  • Other Breast Surgeries

Surgeons: J.-U. Blohmer, O. Camara,
R. Khouri, A. Piatkowski, C. Neeb,
R. Reinemer, J. K. Wagner, C. Weiler

01:15 pm
Lunch Break
01:45 pm

Symposium With kind support of Daiichi Sankyo and AstraZeneca

Spotlight ADCs: An Update for Breast and Gynaecological Cancers

Chairs: J. Sehouli and J.-U. Blohmer

  • ADCs in Breastcancer Therapy: New Opportunities in Early Lines of Therapy
    J.-U. Blohmer
  • ADCs in Gynecological Cancers: Innovations and Opportunities
    K. Pietzner
  • ADCs in the Future Perspective
    V. Kiver
Chairs: S. Kümmel and V. Kiver

Presidential Lecture

02:30 pm
Role of Surgery in Breast Cancer Treatment
J.-U. Blohmer

Trials

02:50 pm
The Most Relevant Clinical Trials (European Perspective, Global Perspective)
S. Kümmel

Lectures

03:05 pm
Invasive Lobular Carcinoma (ILC): Translational Data
S. Oesterreich
03:20 pm
Invasive Lobular Carcinoma (ILC): Clinical Data
M. Karsten
03:35 pm
Endocrine Resistance: Translational Data
A. Lee
03:50 pm
Discussion
S. Oesterreich, M. Karsten, A. Lee
04:00 pm
Coffee Break
Chairs: J.-U. Blohmer and S. Oesterreich

Lectures

04:30 pm
The Role of Germline Pathogenic Mutations and Endocrine Sensitivity
S. Yadav
04:45 pm
Germline Mutations: Digital Tools for Patients and Physicians
D. Speiser
05:00 pm
TNBC: Identifying New Biomarkers for Treatment Escalation and De-escalation
R. Leon Ferre
05:15 pm

Symposium with kind support of Stemline

Extending Endocrine Treatment by Overcoming ESR1 Mutations

Chair: J.-U. Blohmer

  • ESR1 Mutations
    C. Neeb
  • Treatment
    G. Oskay-Özcelik
  • Disscussion and Summary
06:00 pm
End of program
Please note: On Thursday, there will be more lectures in the parallel session Breast Cancer II.
agsdi-vaccine

CMC Crash Course

01:45 to 03:45 pm

Biomarker in Targeted Therapies and Management of Toxicity (ADCs) in Endometrial, Ovarian, and Cervical Cancer
E. I. Braicu, R. Coleman, K. Moore, R. Chekerov, D. Rieke, M. Shahi

agsdi-learn

CMC Master Course

04:00 to 06:00 pm

Surgical and Topographic Anatomy in Ovarian Cancer and Surgical Complication Management in Gynecological Oncology
J. Sehouli, W. Cliby, C. Fotopoulou, J. Neymeyer

Thursday, May 8, 2025 I/II

Breast Cancer Session II

Chair: J.-U. Blohmer
 

Hottest Topics in Clinical Routine and Research

Breast Surgery

08:30 am
Welcome and Introduction
J.-U. Blohmer
08:45 am
BCS vs. ME; R0 vs. R1 Resektion
K. Weiler
09:00 am
Free Flap or AFT in Breast Reconstruction
R. Khouri
09:15 am
Implant or AFT in Breast Reconstruction
A. Piatkowski
 

Panel Discussion

09:30 am
Breast Surgery 1
K. Weiler, R. Khouri, A. Piatkowski
 

Breast Surgery and Around

09:50 am
Gender-affirming Surgery
R. Reinemer
10:05 am
Risk-reducing Surgery: How to Avoid Pitfalls
J.-U. Blohmer
10:20 am
PROs: How to Bring them into Clinical Practice
M. Karsten
 

Panel Discussion

10:35 am
Breast Surgery 2
R. Reinemer, J.-U. Blohmer, M. Karsten
 

Video Session

10:55 am
Breast Cancer Surgery
12:30 pm
End of this Session / Begin of Lunch Break
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Parallel to the Session »Redefining Limits« (Gynecologic Oncology)

Thursday, May 8, 2025 II/II

Cervical Cancer, Endometrial Cancer, and other Solid Tumors


Redefining Limits: Interdisciplinary Approaches in Complex Cancer

Surgery in the Management of Gynecological Malignancies

Chairs: J. Sehouli, R. Armbrust, C. L. Langstraat, S. C. Dowdy

Opening Lectures

08:00 am
Principles and Scheduling of Complex Oncological Surgery in an Interdisciplinary and Interprofessional Setting
J. Sehouli
08:15 am
Options and Limits of Blood Management for Complex Surgeries
L. Kaufner

Session 1
Brain and Ovarian Cancer Metastases

(incl. surgical videos)

08:30 am
Case Report: Cerebellar Metastasis in an Ovarian Cancer Patient
A. Miranda
08:35 am
Brain Metastases – Is there a Role for Surgery in Gynecological Cancer?
P. Vajkoczy
08:50 am
Oligometastatic Disease in Ovarian Cancer – Sporadic or Clinically Meaningful?
K. Pietzner
09:05 am
Discussion

Session 2
Hepatic and Gynecological Cancer Surgery

(incl. surgical videos)

09:15 am
Case Report: Granulosa Cell Tumor Relapse and Major Liver Resection
I. Sterner
09:20 am
Beyond Borders: Joint Cases of Hepatobiliary and Gynecological Cancer Surgeons
W. Schöning
09:35 am
Discussion
09:45 am
Coffee Break

Session 3
Radical Pelvic Surgery

(incl. surgical videos)

10:15 am
Case Report: Enterovaginal Fistula Incervical Cancer Relapse
M. Beck
10:20 am
Radical Pelvic Exenteration – Borders and Limiting Factors
A. Kumar
10:35 am
Complex Reconstruction of the Bladder and Ureter
J. Neymeyer, M. Z. Muallem
10:50 am
Discussion

Session 4
Sarcoma Surgery and Vascular Involvement

(incl. surgical videos)

11:00 am
Case Report: Sarcoma with Bladder and Rectum Infiltration
E. Roser
11:05 am
Principles of Sarcoma and Vessel Surgery
R. Öllinger
11:20 am
Discussion

Session 5
Thoracic Surgery in Gynecological Oncology

(incl. surgical videos)

11:30 am
Case Report: Pleural Effusion and Pleural Carcinomatosis
M. Lee
11:35 am
Role of Thoracic Surgery in Lung and Pleural Metastases
T. Dziodzio
11:50 am
Discussion

Session 6
Surgical Classroom – Advanced Techniques

(dedicated surgical video session)

12:00 pm

Video Session

  • Bowel Anastomosis
  • Ureter Reimplantation and Anastomosis
  • Vessel Reconstruction
12:30 pm
Lunch Break
01:00 pm

Symposium With kind support of GlaxoSmithKline

New Treatment Options for First-line Endometrial Cancer – More Complexity and More Opportunities

Chair: J. Sehouli

  • Introduction
    J. Sehouli
  • Navigating Growing Complexity – An Overview of the Evolving Treatment Landscape and Recent Approvals
    M. R. Mirza
  • Realizing Opportunities for Patients:
    • Patient-orientated Therapy Decision-making
    • MMRp in 1L EC
    • Who Needs ICI? Who Needs ICI + PARPi?
    N. Colombo
  • The Berlin CMC Consensus
    Statement of the Speakers and Summary

    J. Sehouli

Cervical Cancer

Chairs: W. Lichtenegger and N. Abu-Rustum

Presidential Lecture

01:45 pm
Revolution in Cervical Cancer Management, Radical Hysterectomy, Simple Hysterectomy, or Cone Biopsy in Early Stage
N. Abu-Rustum

Trials

02:05 pm
The Most Relevant Clinical Trials (ENGOT, GOG and more) – 10 Minutes Around the World
R. Armbrust

Hottest Debates in Clinical Routine and Research

Primary Local Advanced Cervical Cancer

02:15 pm
Neoadjuvant Chemotherapy
M. McCormack
02:30 pm
Primary Radio-Immuno-Chemotherapy
F. Mehrhof
02:45 pm
Primary Surgery, When, How, When Not?
M. Z. Muallem

Panel Discussion

03:00 pm
What is the Best Therapy Algorithm?
W. Lichtenegger, N. Abu-Rustum, M. McCormack, F. Mehrhof, M. Z. Muallem, B. Monk
03:30 pm
Coffee Break

Endometrial Cancer

Chairs: K. Pietzner and A. Wahner-Hendrickson

Presidential Lecture

04:00 pm
outstanding engagement gynecological oncology colomboEndometrial Cancer Management: Options and Limits to Substitute Chemotherapy?
N. Colombo

Trials

04:20 pm
The Most Relevant Clinical Trials (ENGOT, GOG and More) – 10 Minutes Around the World
L. Chinczewski

Hottest Debates in Clinical Routine and Research

04:30 pm
Primary Chemo-Immunotherapy Plus/Minus PARP Inhibitor
M. R. Mirza
04:45 pm
What are the Predictive Markers for Response to PARP?
E. I. Braicu
05:00 pm
What is the Best Medical Therapy in the Relapse Setting (Endocrine, Immuno After Immuno, Chemo after Chemo, PARP after PARP, Role of ADC)?
A. Wahner-Hendrickson

Panel Discussion

05:15 pm
What is the Best Therapy Algorithm?
K. Pietzner, M. R. Mirza, E. I. Braicu, A. Wahner-Hendrickson
05:45 pm
End of Program
agsdi-learn

CMC Master Course I

01:30 to 03:30 pm

How to Avoid and How to Solve Problems in Breast Surgeries
J.-U. Blohmer, O. Camara, R. Reinemer, S. Paepke, and guests

agsdi-learn

CMC Master Course II

03:45 to 05:45 pm

Basics of Breast Reconstruction – Implant, Flaps, and AFT
J.-U. Blohmer, O. Camara, R. Reinemer, S. Paepke, and guests

Promoting Innovation in Global Women’s Health through Partnership

UNFPA’s WomenX Collective-Charité-Berlin Institute for Health (BIH)

05:30–06:30 pm | Joint Reception (by invitation only)

Chairs:
logo unfpa womenx cobranding vertical webDr. Sara Nasser and
Dr. Andreas Ullrich

Promoting Innovation in Global Women’s Health through Partnership

UNFPA’s WomenX Collective-Charité-Berlin Institute for Health (BIH)

05:30–06:30 pm | Joint Reception (by invitation only)

Chairs:
logo unfpa womenx cobranding vertical webDr. Sara Nasser and
Dr. Andreas Ullrich

Friday, May 9, 2025

Ovarian Cancer

08:25 am
Greeting Words by the FIGO President-Elect
F. Louwen
08:30 am

Live Surgery from 3 operating rooms

Moderation: R. Chekerov, S. Dowdy, W. Cliby, M. Renz

  • En-bloc Resection
  • Peritonectomy
  • Nerve-sparing Techniques
  • Lymph Node Dissection
  • ICG Techniques
  • Perioperative Management

Surgeons: J. Sehouli, R. Armbrust, C. Fotopoulou, M.Z. Muallem

★★★

During Live Surgery:

  • The Most Challenging Case of the Year
    A. Miranda
  • Scientific Highlight of the Year: Exclusive Charité-Mayo Data
12:30 pm
Lunch Break
01:00 pm

Symposium With kind support of AbbVie

Antibody-Drug Conjugates: Facing Platinum Resistance in Advanced Ovarian Cancer

  • Welcome and Introduction
    J. Sehouli, K. Moore
  • A Paradigm Shift in the Treatment of Platinum-resistent Ovarian Cancer
    B. Schmalfeldt
  • New Options and Limits in the Treatment of Platinum-resistant Ovarian Cancer
    F. Hilpert
  • Patient Perspective
    J. Sehouli
  • Panel Discussion: Clinical Trials and Real-World Experiences
Chairs: S. Dowdy and J. Sehouli
 

Presidential Lecture

01:45 pm
Primary Surgery or Interval Surgery – What is the Current Evidence?
S. Mahner
 

Trials

02:05 pm
The Most Relevant Clinical Trials (ENGOT, GOG and more) – 10 Minutes Around the World
R. Chekerov
 

Hottest Debates in Clinical Routine and Research

02:15 pm
Maintenance Therapy: But what?
J. Ledermann
02:30 pm
BRCA/HRD-adjusted Surgery in Primary OC?
M. Renz
02:45 pm
What is the Best Therapy in the HRD Group?
B. Monk
 

Panel Discussion

03:00 pm
What is the Best Therapy Algorithm?
S. Dowdy, J. Sehouli, J. Ledermann, M. Renz, B. Monk
03:30 pm
Coffee Break
Chairs: W. Cliby and R. Chekerov
 

Debate

04:00 pm

Relapsed Ovarian Cancer: Salvage Surgery or Neoadjuvant Therapy?

  • PRO Surgery: J. Sehouli
  • PRO Neoadjuvant: T. Herzog
 

Lectures

Platinum or Chemo Resistance? Time to Change the Definition and the Treatment Algorithm

04:30 pm
ADCs
G. Konecny
04:45 pm
Rechallenge of Previous Therapy
J. Grabowski
05:00 pm
Chemotherapy-free Approaches
S. Banerjee
05:15 pm
Best Supportive Care Only!
E. Roser
05:30 pm
Palliative Surgery
C. Fotopoulou
05:45 pm
Discussion
06:00 pm
End of Program
agsdi-learn

CMC Master Course

04:30 to 06:30 pm

Prerehabilitation, Fast-track Rehabilitation, ERAS, Minimally Invasive Complication Management
S. Dowdy, A. Kumar, J. Sehouli, M. Lee

Saturday, May 10, 2025

Cross Talk and More

Chairs: A. Ullrich and S. Nasser

Presidential Lecture

09:00 am
How We Can Improve Women’s Health
D. Sood
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Lectures

09:20 am
Screening for Cardiovascular Diseases in Women
U. Landmesser
09:40 am
Biomarker in Targeted Therapies: Yesterday, Today, Tomorrow
K. Moore
10:00 am
How to Translate Guidelines into Regions with Limited Resources
D. Cibula
Chairs: D. Cibula and J.-U. Blohmer, P. Wimberger

Learning Across the Diseases

Endocrine Therapy: What is the Code in Breast Cancer, What in Gynecological Malignancies?
10:20 am
  • Gynecologic Cancer: M. Beck
10:35 am
  • Breast Cancer: K. V. Giridhar
10:50 am
  • Urologic Cancer: M. De Santis
PARP Inhibitors: What is the Code in Gynecologcial Malignancies, What in Breast Cancer, What in Other Solid Tumors and Who are the Best Candidates?
10:55 am
  • Gynecologic Cancer: A. Mustea
11:10 am
  • Breast Cancer: D. Speiser
11:25 am
  • Pancreatic Cancer: S. Stintzing
Checkpoint Therapy: What is the Code in Gynecologcial Malignancies, What in Breast Cancer, What in Other Solid Tumors?
11:30 am
  • Gynecologic Cancer: K. Pietzner
11:45 am
  • Breast Cancer: V. Kiver
12:00 pm
  • Liver Cancer: B. N. Ostendorf
12:05 pm

Lunch Break

During Lunch Break:
Poster Session

ADCs: What is the Code in Gynecologcial Malignancies, What in Breast Cancer, What in Other Solid Tumors?
01:05 pm
  • Gynecologic Cancer: F. Heitz
01:20 pm
  • Breast Cancer: C. Neeb
01:35 pm
  • Other Solid Tumors: A. Kurreck

Lectures

01:40 pm
Leveraging AI to Decode and Replicate Cellular Architecture: A Vision for the Future
S. Quake
02:00 pm
AI Biomarkers for Precision Oncology
J. N. Kather
02:15 pm

New Options in the Management of Malignant Ascites

  • Pathophysiology and Clinical Aspects of Ascites
    K. Pietzner
  • Focus on Ovarian Cancer
    J. Sehouli
  • Focus on Other Gynecological and Non-Gynecological Malignancies
    P. Wimberger
  • Panel Discussion

Closing Session

03:00 pm
3 Best Posters: Discussion and Acknowledgment Poster Awards
03:15 pm
Closing Words and Farewell
J.-U. Blohmer and J. Sehouli
03:30 pm
End of Program
agsdi-doctor

CMC Cadaver Course

08:00 to 12:00 pm

Gynecology
M. Z. Muallem, A. Miranda, T. Jöns, O. Camara

Welteierstockkrebstag am 10.05.2025

Status: 03/2025; May be subject to change.

Charité Mayo Conference